트리클로잔과 자몽종자추출물(GFSE)과 Eucalyptus oil 및 플라보노이드를 배합한 세치제의 구취예방효과에 관한 연구
A study on the halitosis reduction by dentifrice containing triclosan, GFSE, eucalyptus oil and flavonoid
배광학, 노승학, 차창선,
소속 상세정보
배광학 ( ) - 서울대학교 치과대학 예방치학교실
노승학 ( ) - 서울대학교 치과대학 예방치학교실
차창선 ( ) - 서울대학교 치과대학 예방치학교실
KMID : 0355420020260020251
Abstract
The aim of this study was to assess the effect of the dentifrice containing 0.2% triclosan, 0.1% Grapefruit seed extract(GFSE), 0.19% Eucalyptus oil and 0.25% flavonoid on malodor. The negative control contained no antibacterial agents. In vivo study, the case control, double-blind and crossover design was used, and 40 healthy subjects aged from 20 to 30 participated. On baseline, subjects received the same toothbrushes and were requested to clean their teeth three times daily. Halitosis level was determined by halimeter. Halitosis levels of all subjects were determined at baseline, 1 hour after mouthrinsing with slurry of dentfrice and distiled water after 1week and 3 weeks. After 6weeks of refreshing period, experimental and control group were changed each other, and halitosis levels of all subjects were determined again. 1 hour after mouthrinsing with slurry of dentfrice and distiled water mean halitosis level was not different between experimental and control group(p) 0.05). But, mean halitosis level of experimental group was lower than control after 1 week and 3weeks(p (0.05). As a result, it was suggested that the dentifrice which contained 0.2% triclosan, 0.1% Grapefruit seed extract(GFSE), 0.19% Eucalyptus oil and 0.25% flavonoid be effective on halitosis.
키워드
구취;세치제;Encalyptus oil;플라보노이드;트리클로산;halitosis;dentifrice;flavonoid;triclosan
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